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Pharmaceutical manufacturing

Clinic application and development of slight acidic water

The rapid globalization make microbe contagion spread more place in short time,meanwhile,the contagious condition of medical system is complicating.The hospital contagious management is relative with sterilization and disinfect.This situation need to higher the requirement of disinfect and sterilization.The employee from industry relative take the pursuit target for researching safe and lower polluted disinfectant.In 1990,acidic electrolyzed water is revealed in Japan,and scholars research its effect and safeness.In 2002,slight acidic water is designed as food disinfectant.

Afterwards,other domain has developed the relative medical industry.Here is the description about mechanism,property, disinfect effect and application.

1.The introduction of electrolyzed water

1.1 The electrolyzed water generationAcidic electrolyzed water is kind of electrolyzed water.Acidic electrolyzed water whose PH value is less 7 is generated from electrode with diluted salt water.Acidic electrolyzed water is named EOW(electrolyzed oxidizing water) in 2002 edition.The electrolyzed water is generated by electrolyzed concentration less0.01%salt water in two-room and three-separation-membrane where oxygen,chlorine and H+ in positive pole by chlorine reacting with water,and where OH and H in value more 7 in negative pole.Slight acidic electrolyzed water is generated from concentration2%-6% HCL solution by the electric pressure 2 V in the non-separation-membrane or one-room electrolyzed room.Chlorine reacts with water to be HCL and HCLO,and hydrogen in negative pole.

1.2The advantage of electrolyzed waterElectrolyzed water has the disinfect character of high-effectiveness,rapidity, low cost and broad-spectrum.In contrast with EOW,here are characters of slight acidic electrolyzed water:the HCL as material is low costing.The equipment can continuously be operated without any residue because of evaporation in air.

Here is low concentration of dissolved oxygen,ozone formation and chlorine which has the disinfect effect without any ozone and oxygen even higher chlorine oxides alike HCIO.The electrolyzed water is transparent non-collective liquid including HCLO.Which is odorless and less corroded and less harm for people in PH value 7.Electrolyzed water can reduce water after functioning without any salt.here is no adverse of salt crystal and concentration in dry condition.Electrolyzed water is ideal in medical system,because it is no odor and no vocational protection.

1.3 The reserve of electrolyzed waterSlight acidic water easily decomposes in face of sun,and the effective chlorine is 78%after 40 days in closet surrounding.The electrolyzed water is reserved in closet surrounding.

1.4 The toxin of electrolyzed waterIn Japan,electrolyzed water as food disinfectant shows that,besides food experiment,it is normal and certain in series of experiment.

1.5 The corrosion of electrolyzed waterThe electrolyzed water in PH value 5.0-6.5 as accessible with neutral value without any corrosion for any materials.

2.The disinfect function of electrolyzed water

2.1 The disinfect base and mechanismThe disinfect base of electrolyzed water is HCLO,which can hurt the cell membrane to make protease,RNA and DNA not exert normal biochemical activity leading to die,and to reduce water in touch with organic compound and microbes.The HCLO proportion is varied with PH value.the CIO volume raise in alkali,chlorine volume lower in acid.HCIO disinfect effect is 80-100 times than CIO.The PH value of HCIO in acidic electrolyzed water is high,the PH value is 5.0-6.5 where 97% acitive chlorine is HCIO.So the low concentration electrolyzed water can develop good disinfect effect.

2.2 The broad-spectrum,high-effectiveness,rapidity character for electrolyzed water.The microbe sensitivity for disinfect factor from high to low are:pro fat virus,bacterial reproduction,hydrophilic virus,mycobacterium and spore.

In 1987, Japan developing disinfectant for MRSA has good effect,and apply into the medical industry.The disinfect effect of EOW is good in China. 2002 edition and specification for hospital infection monitoring in 2009 allow it to disinfect skin mucous membrane and intestinal endoscopy.The disinfect effect research of the slight acidic water is not wholly developed.In some researches,the electrolyzed water has the disinfect effect on the FLU and bacterial reproduction in short time.In 20 degree,it needs time to inspect the index: the HCLO solution with effective chlorine 100mg/l need 15 seconds,but the electrolyzed water need 5 minutes.The disinfect effect of electrolyzed water can be higher with the water temperature,and can be lower with the organic compound which is similar with EOW.Here is special disinfect effect research for 6 species microbe groups.Electrolyzed water has the effect on refraining from growth for 6 species.In 30 degree,102-103FU/MLspore solution reacts with electrolyzed water in 10 minutes,the sprout generation lower by 1/10-1/100.the experiment of electrolyzed water killing salmonella enteritidis shows that in the same effective chlorine volume,it is same with the disinfect effect of EOW.In the 3 temperatures(4,200,45)the killing rate for salmonella enteritidis is 100% in the electrolysis function (including 4mg/l effective chlorine)in 2 minutes.

3.The application of electrolyzed water

3.1 The application of electrolyzed water in food industry .It is good effective and friend-environmental for electrolyzed water with low effective chlorine as the ideal vegetable disinfectant.In applied practice,the electrolyzed water is more high-effective than NACLO In food and vegetable disinfection,and surmount the disadvantage of high residual chlorine,diffcult treatment and harm substance from NACLO,and can kill out staphylococcus aureus and escherichia coli,and kill the vibrio sp. And vibrio vibrio caused by severe food poisoning in 30 minutes.In the disinfect of vegetable and food,it can de used by rinse and fume without any affect of color and quality.It can sustain with effective chlorine volume in closet in application with the seal fluid in food processing pipe and soaking disinfect.

3.2 Slight acidic water applied with air disinfect The electrolyzed water is no difference in flavor with the running water.That can inactive fungi,microbe,FLU and coronavirus and so on.Here is air disinfect in class where is someone here and inspect the humidity,comfort and discomfort.The result shows that elelctrolyzed water is of good disinfect effect.In Japan,electrolyzed is used in hospital,canteen,office and facilies.In medical,the usual disinfect meaure are ultraviolet,chemical medicine and so on,which nees long time and harmful for human body.It is maximum effect on the dental disinfect for electrolyzed water.

3.3 Slight acidic water applied with object surfaceIn clinic operation,the disinfection liquid,which has severe odor, corrosion,pollution and irritation for throat and mucoud membrane of eye,is used to clean and cure to disinfect.

EOW as the green and friend environment disinfectant is extensively used on the surface of clinic object.in view of advantage of light acidic electrolyzed water with EOW,that is developed further to research the disinfect effect of disinfect effect in medical domain.It is noticed that light electrolyzed water is accessible in compare with EOW.

3.4 The electrolyzed water is expected the other medical domainEOW as one of electrolyzed water has good effect on disinfecting inflammation and medical staff’s hand skin,oral medical and endoscope,but the slight acidic water is not.

That is high-effective and rapid disinfectant to reduce water in oxidizing and reducing reaction.Slight acidic electrolyzed water is the ideal disinfectan in medical system without any pollution.

4. ConclusionWith the execution of sustainable development,it is inevitablefor our country to build the economical and friend-environmental society.People-orientated and friend-environmental disinfectant take the clean air and surrounding to medical staffs.Slight acidic water as the friend-environmental disinfectant has broad future and deeply has experiment to research the applied value in medical circle as soon as possible.

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